The Healing Co Canada defines cachexia as a multifaceted condition characterized by persistent muscle loss that cannot be completely reversed through typical nutritional support, leading to a decline in functionality. It may be masked by excess weight, obesity, edema, or tumor mass. Anorexia, which is a decrease in appetite, is frequently observed in cancer patients, although its precise prevalence remains unclear.
When cachexia primarily results from diminished intake, it is termed cancer-related cachexia and anorexia syndrome (CACS), which encompasses muscle wasting, lipolysis, and reduced food consumption, distinguishing it from simple cachexia.
Some researchers suggest that cannabis from The Healing Co Canada can enhance appetite and alleviate nausea in cancer patients.
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Key Takeaways:
- THC capsules may assist cancer patients in increasing their food intake and reducing sickness, thereby enhancing their overall quality of life.
- Studies indicate that cannabis influences brain cells that regulate hunger, potentially addressing appetite issues in cancer patients and others.
- THC capsules are precise, convenient, private, and provide long-lasting effects, making them ideal for medical marijuana users who prefer not to smoke.
Cancer Cachexia and Anorexia Syndrome
Cachexia is identified by notable weight loss resulting from the depletion of muscle and fat, frequently seen in patients with severe diseases such as heart failure, HIV/AIDS, COPD, kidney failure, and particularly cancer.
This typically occurs alongside anorexia, defined as a decreased appetite leading to at least a 5% reduction in body weight. Together, they constitute cancer anorexia-cachexia syndrome (CACS).
Patients hospitalized with cancer often exhibit poor dietary intake, with nearly half being malnourished or at risk. Cachexia not only diminishes patients’ quality of life but also impedes treatment and can hasten the end of life. Its prevalence significantly increases as death approaches, with cachexia cited as the primary cause of death in over 20% of cases.
Despite its frequent occurrence, CACS often goes unnoticed and untreated in clinical environments due to unclear definitions, diagnostic criteria, classification systems, and lack of approved therapies. Clinicians evaluate a patient’s nutritional status using various metrics, such as body weight, skin fold thickness, and mid-arm circumference, although body weight is commonly relied upon, often using inappropriate reference weights.
Treatment
Improving nutrition is the most evident approach to addressing anorexia, but evidence supporting its effectiveness is limited. For cancer patients, nutritional care includes:
- Dietary Counseling
- Oral Supplements
- Enteral and Parenteral Nutrition
The success of these interventions varies based on the type and stage of cancer.
Pharmacological Approaches
Currently, there are no validated medications for treating Cancer Anorexia-Cachexia Syndrome (CACS), but some drugs are administered off-label or are undergoing clinical trials. These medications are categorized into four groups based on their mechanisms:
- Appetite Stimulants
- Cytokine Modulators
- Anabolic Agents
- Combination Therapies
Moreover, megestrol acetate, a progestin, is employed independently due to its unclear mechanism of action.
Cannabis in Medicine
The potential benefits of cannabis could enhance the lives of cancer patients, offering hope for those suffering from cachexia, a condition characterized by appetite loss and malnutrition. It provides relief without intoxicating effects, positioning it as a promising option for these patients.
Various cannabis formulations with different effects are available, including inhaled THC for rapid onset and short-lived effects, and orally ingested THC for slower absorption and prolonged effects. Sublingual administration offers rapid onset and lasts 2 to 4 hours.
Clinical Trial
A study conducted by researchers in Israel and the United States evaluated how cannabis capsules impact CACS in advanced cancer patients. This research has significant implications for treating appetite disorders faced by cancer patients, individuals with anorexia, and potentially those with obesity.
Methods
The study utilized cannabis capsules containing two types of oil-based compounds. Participants were treated with 10 mg doses twice daily for six months, which consisted of 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).
If participants faced side effects, the dose was reduced to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). Weight measurements were taken at each doctor’s visit. The primary goal was for participants to gain at least 10% more weight than their initial weight.
Results
Out of 24 patients who consented to participate, 17 began treatment with cannabis capsules. However, only 11 continued taking the capsules for over two weeks. Ultimately, 3 out of 6 patients who completed the treatment met the primary goal of achieving at least 10% more weight. The weight of the remaining three patients remained unchanged.
Tumor necrosis factor-α (TNF-α), an inflammation marker, decreased following treatment. Patients reported improved appetite and mood, along with reduced pain and fatigue.
Despite several challenges, this preliminary study demonstrated a weight gain of 10% or more in 3 out of 17 patients (17.6%) taking daily doses of 5 mg without notable side effects. These findings encourage further investigation in larger, controlled studies involving cannabis capsules for patients with CACS.
Cannabis Capsules
If you enjoy edibles, cannabis flowers, or classic pre-rolls, exploring new ways to experience cannabis is always appealing.
THC capsules represent a recent addition to the cannabis market. These capsules contain a specific dose of THC, created from a concentrated cannabis extract and a neutral oil. They are similar to cannabis tinctures but in capsule form (also referred to as cannabis oil capsules or THC pills).
Key Components
- Cannabis Extract: This concentrated extract is obtained from the cannabis plant using a method selected by the manufacturer. THC capsules are rich in THC, though some may exclusively contain CBD or varying CBD/THC ratios.
- Neutral Oil Suspension: THC is not soluble in water; thus, it is suspended in oil for optimal absorption by the body. Common oils used include medium-chain triglycerides (MCT oils), which assist in digestion and absorption.
Benefits
Both medical marijuana patients and recreational users can gain advantages from cannabis capsules. They provide:
- Convenience: Taking a cannabis capsule is as simple as any other oral supplement. Just swallow it with water, no fuss.
- Precision Dosage: For medical users, precise control over cannabinoid intake is vital for achieving desired effects. With THC capsules, each dose is calibrated, eliminating uncertainty.
- Smoke-Free Option: Many individuals prefer to avoid smoking or vaping for personal or health reasons. THC capsules present a smoke-free alternative, suitable for those with respiratory concerns.
- Longer Effects: Capsules generally offer longer-lasting effects compared to smoking or vaping, making them ideal for sustained symptom relief over several hours.
Cannabis Capsules vs. Other Forms of Medicinal Cannabis
| Aspect | Cannabis Capsules | Other Forms of Medicinal Cannabis |
| Dosing | Precise dosing with each capsule | Dosing may vary based on the consumption method (e.g., smoking, vaping, edibles) |
| Consumption | Oral ingestion | Smoking, vaping, edibles, tinctures |
| Effects | Longer-lasting, gradual onset | Immediate onset, shorter duration |
| Effects on Appetite Stimulation | Gradual stimulation | Immediate stimulation |
Place a Medical Cannabis Delivery Order Conveniently
With the rising demand for reliable cannabis delivery services, online dispensaries provide a seamless solution. From same-day cannabis delivery to high-quality cannabis products, these dispensaries offer a diverse range of options to meet every preference and need.
If you are searching for cannabis flowers, pre-rolls, edibles, or vape pens, you can conveniently explore The Healing Co Canada’s finest marijuana products sourced from top-quality marijuana plants. Shop for your preferred THC products from the comfort of your home.
So why delay? Experience same-day delivery today.
Frequently Asked Questions
What are the different types of capsules?
Another benefit of cannabis pills/capsules is their versatility—formulators can design various capsule types for consumers to choose from, allowing you to find capsules that suit your preferences.
- 1:1 Capsules: These capsules provide an equal ratio of THC to CBD per dose. They can be crafted using sativa or indica strains and come in different concentrations such as 5 mg, 20 mg, 50 mg, or 100 mg of cannabinoids per capsule.
- 3:1 Capsules: These capsules deliver a ratio of 3 parts CBD to 1 part THC per dose.
- THC Capsules: These capsules contain THC exclusively, with varying concentrations per capsule, derived from different Sativa or Indica strains to offer specific effects.
- CBD Capsules: These only contain CBD, devoid of THC, preventing mind-altering effects. They are intended for individuals seeking the benefits of CBD alone.
How do capsules interact with your body?
- The outer shell of the capsule disintegrates in your digestive tract after consumption.
- The contents of the capsule are absorbed into the bloodstream.
- THC (and other cannabinoids) are metabolized in the liver.
How long does it take for cannabis capsule effects to kick in?
Typically, THC capsules take around 90 minutes to start exhibiting effects. The effects can last from 5 to 12 hours, gradually decreasing in intensity. In comparison to inhaled cannabis, capsule effects generally last about twice as long on average.
However, experiences may vary due to factors such as age, medications, personal cannabis tolerance, and cannabinoid composition. Some users also report different effects based on specific cannabinoids present, potentially due to the “entourage effect.”
How to mail order marijuana?
To mail order recreational cannabis, locate a trustworthy delivery service online that offers quality cannabis products. Once you select your products, opt for “order cannabis delivery,” and a delivery driver will securely deliver your order. Ensure the service is reputable for a smooth purchasing experience.
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